The titular hero of the game is Fred, a private investigator in the town of Hope Falls. There's bad business afoot in town, though, because a ruthless mob boss by the name of Pitt has moved in and bought up all the businesses in town, using them as fronts for an array of illegal activity. To power his empire, Pitt built a nuclear power plant, but he cut corners and all kinds of toxic waste began to poison the town. Eventually, all sorts of crazy mutants and zombies infested the place, turning the once quaint slice of Americana into a nightmarish landscape of death and destruction.