The biggest feature of the 1.0.4 (or 1.0.2 MoD) update is that the Homebrew is playable in English. That is something that wasn't possible in the previous versions. The original language of this Homebrew is Russian, so not only the Russian speaking gamers can enjoy it, but almost everyone. Also what's new in the latest update is the look. The intro is changed, and a new XMB look is also added. So now we can enjoy science on our PSP in English with a much improved look.
Now what do I need to do? Mix and match the elements to get new ones which are also to be used in alchemical chain. The point is simple: initially with four basic elements, and combining them together to open all the available items. The four elements are fire, water, land and air and with these elements you should be able to make plenty of other elemental combinations. Too bad I know nothing about science...