What would it take to stop you from gaming? If you said being bedridden, hooked up to various machines with limited use of your limbs, then you are a complete wuss. Just ask PlayStation 3 forum poster KitsuneYume, who built a PS3 controller he works with his entire body, including his mouth. While the setup won't win any product design awards, it allows Kitsune there access to 20 out of 25 possible controller functions using 16 switches and a joystick he controls with his tongue, all wired into a standard PS3 controller.
The main reason I put this on the PlayStation website was to show people that even the most limited person can still enjoy console gaming just as much... anyone else. the controller was pretty easy to make except for converting the analog signals into digital signals for when I use the various switches. this took about two months to build and get working effectively.